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A recent mini-review highlights some of the infrequently encountered complications of TNP

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In 1950, Chaiken et al reported a case of fever, hepatitis, and exfoliative dermatitis in a patient taking phenytoin, which he/she described as Dilantin (diphenylhydantoin) hypersensitivity.[3] However, it took another 20 years to reach a consensus that phenytoin could produce a characteristic hypersensitivity syndrome.[4] After the introduction of hydantoins, several drug reactions, including rashes, fever, and eosinophilia, were reported

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